Endocrine Abstracts

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs.Dokuz Eylul University Adrenal Tumours Study Group database includes 596 patients by January 2016. Briefly, there are 332...

Introduction: Natural history of adrenal incidentalomas has not been totally understood. Current data from subjects with adrenal incidentalomas demonstrated an increased rate of metabolic disturbances and cardiovascular risk. It has been shown that subjects with subclinical cortisol excess were more susceptible to diabetes, hypertension, and obesity. However, there is no data regarding prospective cardiovascular risk evaluation in subjects with subclinical Cushing’s syndr...

Introduction: Acromegaly is a rare disease characterized by GH and IGF1 hypersecretion and increased cardiovascular mortality. Ultrasonographic measurement of carotid intima media thickness (CIMT) gives substantial information about early atherosclerosis. We aimed to evaluate CIMT and its determinants in a group of acromegaly patient.Patients and methods: Forty-four acromegaly patient and 43 age, sex and body mass index (BMI) matched healthy controls wer...

It has been previously shown that adrenal adenomas are associated with a variety of metabolic disturbances like glucose intolerance and obesity. The aim of this study is to demonstrate the risk of non-alcoholic fatty liver disease development in subjects with adrenal incidentalomas.Among 302 subjects referred between 2001 and 2008 for the evaluation of incidentally discovered adrenal mass, 150 subjects with appropriate data were included. Computed tomogr...

Adrenal adenomas are characterised with metabolic disturbances. The aim of this study is to demonstrate the changes in some metabolic and anthropometric parameters after 24 months follow up in subjects with non-functioning adrenal adenomas.Subjects referred between 2001 and 2008 for the evaluation of adrenal tumours were included. Computed tomography (CT) was the initial radiological intervention. Initial hormonal evaluation included 1 mg or 2 day 2 mg d...

Increased use and improved technology of imaging procedures have led to increased recognition of adrenal incidentalomas. The aim of this study is to evaluate the natural course of benign adrenal tumours in terms of tumour growth and hormone secretion.Subjects referred between 2001 and 2008 for the evaluation of adrenal tumours were included. Computed tomography (CT) was the initial radiological intervention. Initial hormonal evaluation included 1 mg or 2...

Introduction: Thymic hyperplasia is a rare manifestation of Graves disease. In this report, we describe a female with Graves’ disease and a neck mass that was associated with thymic hyperplasia.Case report: A 28-year-old woman was referred to our division for the evaluation of palpitations. Thyroid function tests were associated with thyrotoxicosis. Thyroid receptor antibody (TRAb) was found to be 22.3 U/l (positive: >14 U/l). Sonography showed ...

The mechanism of atherosclerosis in patients with subclinical hypothyroidism (sHT), which has been partly attributed to lipid abnormalities, is still controversial. There is substantial evidence that ox-LDL plays an important role during the atherosclerosis process and paraoxonase-1 (PON-1) significantly inhibits generation of lipid peroxidation and thus plays a role in against atherosclerosis. The aim of the study was evaluate qualitative changes in lipoprotein metabolism, hs...

Fine needle aspiration biopsy is the cornerstone for cytologic evaluation of thyroid nodules. Thyroid nodule prevelance increases with age, however there is no cytologic study exclusively from geriatric patients.We examined the thyroid fine needle biopsy records taken from patients age 65 years or older between January 2006 and June 2009 at Dokuz Eylul University Hospital; and reviewed the cytological results of this group.We analy...

Objective: Endogenous hyperthyroidism is associated with altered coagulation. The aim of the present study is to investigate the effect of levothyroxine (LT4) suppression treatment for benign thyroid nodules on coagulation system.Design: Prospective case-control study.Patients: Thirty consecutive euthyroid pre-menopausal women with nodular goitre disease and 28 healthy controls were included in the study.Meas...